Multiplexed electrochemical immunosensor for detection of celiac disease serological markers
نویسندگان
چکیده
منابع مشابه
Electrochemical immunosensor for the diagnosis of celiac disease.
A novel electrochemical immunosensing strategy for the detection of antibodies to tissue transglutaminase (tTG) in human serum is presented. The proposed immunosensor consists of the immobilization by physical adsorption of tTG from guinea pig liver on graphite-epoxy composite (GEC) electrodes. After the reaction with the human serum (containing the specific antibodies in the case of celiac dis...
متن کاملElectrochemical Immunosensors for Celiac Disease Detection
Unfortunately, a high percentage of people with celiac disease (CD) is not yet diagnosed. The disease could begin at any age and the different produced symptoms may complicate the diagnosis, delay the treatment and worsening the living conditions of the patient. Therefore, early diagnosis of the disease when patients have few or not symptoms is really important and can help to improve the patie...
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Celiac disease is a gluten-induced autoimmune enteropathy characterized by the presence of tissue tranglutaminase (tTG) autoantibodies. A disposable electrochemical immunosensor (EI) for the detection of IgA and IgG type anti-tTG autoantibodies in real patient's samples is presented. Screen-printed carbon electrodes (SPCE) nanostructurized with carbon nanotubes and gold nanoparticles were used ...
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The first electrochemical immunosensor (EI) for the detection of antibodies against deamidated gliadin peptides (DGP) is described here. A disposable nanohybrid screen-printed carbon electrode modified with DGP was employed as the transducer's sensing surface. Real serum samples were successfully assayed and the results were corroborated with an ELISA kit. The presented EI is a promising analyt...
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A novel electrochemical immunosensor array for the simultaneous detection of multiple tumor markers was developed by incorporating electrochemically addressing immobilization and one signal antibody strategy. As a proof-of-principle, an eight-electrode array including six carbon screen-printed working electrodes was used as a base array for the analysis of two important tumor markers, carcinoem...
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ژورنال
عنوان ژورنال: Sensors and Actuators B: Chemical
سال: 2013
ISSN: 0925-4005
DOI: 10.1016/j.snb.2012.09.019